Midazolam Structure

1 a short review is given of the basic chemical development in the field of classical and annelated benzodiazepines distinguishing between pro drugs and directly acting compounds.

Midazolam structure. This drug is unique from others in this class due to its rapid onset of effects and short duration of action. The pk of midazolam is 6 15 which permits the preparations of salts to be water soluble. Molecular formula c 18 h 13 clfn 3. It is also useful for the treatment of seizures.

Midazolam marketed under the trade name versed among others is a benzodiazepine medication used for anesthesia procedural sedation trouble sleeping and severe agitation. It belongs to a class of drugs called benzodiazepines. The basicity of its imidazole ring nitrogen which allows water soluble salts and well. Midazolam hydrochloride is the hydrochloride salt of a short acting benzodiazepine derivative with an imidazole structure and anxiolytic amnestic hypnotic anticonvulsant and sedative properties.

It works by inducing sleepiness decreasing anxiety and causing a loss of ability to create new memories. Midazolam can be given by mouth intravenously or injection. Monoisotopic mass 325 078217 da. Average mass 325 767 da.

Midazolam maleate usan 8 chloro 6 o fluorophenyl 1 methyl 4h imidazo 1 5 a 1 4 benzodiazepine maleate 1 1 midazolam maleate salt. Midazolam c18h13clfn3 cid 4192 structure chemical names physical and chemical properties classification patents literature biological activities safety. Midazolam is a short acting hypnotic sedative drug with anxiolytic muscle relaxant anticonvulsant sedative hypnotic and amnesic properties. 2 some properties of midazolam that are of special interest for its practical use are discussed such as.